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SHOP AYAHUASCA RETREATS BLOG

Plant Variety and Colon Cancer: What a New Phytochemical Study Suggests

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Finn Ashton
September 17, 2026


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Think back to what you actually ate yesterday. Not what you meant to eat — what actually landed on the plate. A handful of blueberries with your oats? A side salad you almost skipped? Lentils in a soup, some pumpkin seeds on top, maybe a mug of green tea while you answered emails? If any of that sounds familiar, you were quietly loading up on phytochemicals — the compounds plants make to protect themselves that seem to do useful things for us too.

A study published earlier this year put a striking number on the payoff. People whose diets scored highest for phytochemical-rich foods had roughly 52% lower odds of colorectal cancer than people whose diets scored lowest. That’s the kind of headline that deserves both attention and a little skepticism, so let’s unpack it — and then talk about why any of this matters if you’re preparing for a plant-medicine retreat, coming home from one, or just trying to eat like you mean it.

What the researchers actually looked at

The study compared 980 adults — half diagnosed with colorectal cancer, half not — and asked them to fill out detailed food questionnaires. From those answers, researchers calculated something called a Dietary Phytochemical Index, a score that estimates how much of a person’s daily calorie intake comes from plants rich in these protective compounds.

Phytochemicals aren’t a single thing. The umbrella covers polyphenols, flavonoids, carotenoids, phytosterols, and a long tail of lesser-known compounds. You’ll find them in berries, leafy greens, beans and lentils, whole grains, nuts, seeds, herbs, spices, cacao, coffee, and tea. Different plants carry different mixes, which is why nobody serious in nutrition science is still hunting for one heroic superfood.

The highest-scoring participants didn’t just have lower cancer odds. They also showed friendlier markers of inflammation and oxidative stress — two processes that turn up over and over in research on chronic disease. The obvious caveat: this is an observational study. Some participants already had cancer when their diets were measured, so we can’t say the phytochemicals prevented anything. What we can say is that a pattern keeps showing up, in study after study, and it’s pointing in the same direction.

Why variety seems to beat any single ‘superfood’

Here’s the thing the wellness industry keeps getting wrong: it wants a hero. One berry. One mushroom. One powder in a $60 tub. The research just doesn’t cooperate. What consistently helps is the range of plants someone eats over a week, not the intensity of any one item.

The reason is chemical. Blueberries bring anthocyanins. Broccoli brings sulforaphane. Turmeric brings curcumin. Green tea brings catechins. Black beans bring their own polyphenol profile. Each compound seems to do slightly different work in the body — some are antioxidants, some modulate inflammation, some feed the specific gut bacteria that keep the colon lining calm. Eat only one of them and you get one narrow slice of the benefit. Rotate through many and the effects appear to stack.

There’s a rough goal that keeps popping up in gut-health research: thirty different plant foods a week. That sounds like a lot until you count herbs, spices, nuts, seeds, and beans — a bowl of chili with cumin, cilantro, onion, garlic, tomatoes, kidney beans, black beans, and a squeeze of lime is already eight before you’ve touched a vegetable side.

Single white datura flower at night, deep black around it | ShopAyahuascaRetreats

Simple ways to widen the plant mix without becoming that person

You don’t need a spreadsheet or a supplement stack. You need a slightly wider rotation and slightly less autopilot at the grocery store. A few honest starting points:

  • Rotate breakfasts. If oatmeal is your default, alternate the toppings — walnuts and pear one day, almond butter and raspberries the next, tahini and banana the day after.
  • Sneak in legumes. A can of lentils goes into almost any soup, grain bowl, or pasta sauce without changing what the meal feels like. Chickpeas roast up as a crunchy topping in twenty minutes.
  • Buy the unfamiliar vegetable. Pick one you never buy — kohlrabi, radicchio, delicata squash, purple sweet potato — and give it one shot. Worst case, you throw it in a stir-fry and move on.
  • Keep seeds on the counter. Pumpkin, sunflower, sesame, chia, hemp, flax. A tablespoon on top of anything savory adds compounds you weren’t otherwise getting.
  • Rethink drinks. Green tea, black tea, matcha, hibiscus, cacao, coffee — all bring their own polyphenols. Water is fine, but a mug of something plant-derived earns you extra credit.

The goal isn’t perfection. It’s exposure. You’re trying to feed a wider bacterial community in your gut and hand your body a broader set of raw materials, not audition for a magazine cover.

Why this matters if you’re heading into or out of a plant-medicine retreat

If you’re here because you’re researching ayahuasca, San Pedro, or a psilocybin retreat, the phytochemical conversation should actually be interesting to you. Traditional ayahuasca dieta — the food restrictions the shipibo and other Amazonian traditions ask participants to follow — tend to strip the plate down to simple, bland foods: plantain, rice, some fish, boiled vegetables. Salt, sugar, fermented foods, pork, alcohol, and aged foods usually come off the table for a stretch. There are safety reasons (the MAOI activity in the ayahuasca brew makes certain foods risky) and there are ceremonial reasons (the fewer competing inputs, the clearer the plant’s voice, in the traditional view).

But the dieta ends. Integration doesn’t. In the weeks after a ceremony, when the emotional cracks are still open and the nervous system is recalibrating, what you feed yourself matters more than usual. Chronic inflammation dulls mood, disrupts sleep, and clouds the kind of insight-work integration depends on. Loading the post-retreat weeks with colorful plants, plenty of fiber, and a wide phytochemical rotation isn’t just cancer-risk arithmetic — it’s giving your gut, your mood, and your brain the substrate to actually consolidate whatever you saw in ceremony.

And on the other side, the pre-retreat window is a good moment to start too. Facilitators often ask participants to reduce processed food, alcohol, sugar, and caffeine in the two to four weeks before a retreat. That’s an opening. Fill the gap with variety rather than deprivation and you arrive lighter, clearer, and less likely to spend the first ceremony purging a week of drive-through.

How to read studies like this without getting whiplash

A 52% reduction in odds sounds enormous, and it is — but odds ratios in observational studies always deserve a second look. The people who eat the widest range of plants also tend to move more, sleep better, smoke less, and drink less. Statisticians try to adjust for those factors, but no adjustment is perfect. So treat the number as a strong signal, not a promise.

What makes this line of research trustworthy isn’t any single study. It’s the consistency. Population studies, mechanistic lab work on individual phytochemicals, and gut-microbiome research keep converging on the same story: diverse plant intake is protective across a range of chronic diseases, and colorectal cancer is one of the clearest examples. The exact size of the effect will vary from study to study. The direction doesn’t.

Pitcher plant nestled in moss, water collected inside the cu... | ShopAyahuascaRetreats

The quiet takeaway

Nobody’s asking you to become vegan or memorize a list of flavonoids. The suggestion is smaller and more doable: widen the rotation. Add one new plant food to the shopping list this week. Put seeds on things. Drink tea. Cook with more herbs. The gut and the brain are more connected than most people were taught — take care of one and the other tends to thank you.

For readers whose interest in this stretches beyond diet into deeper healing work, a range of curated ayahuasca and plant-medicine retreats can be browsed on our marketplace here — many of them build nutrition, dieta, and integration meals directly into the program. Whatever you decide, the plate in front of you tonight is a fine place to start.




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Finn blends his love for plant medicine, traveling, and ceremony. He facilitates transformative ayahuasca experiences during his journeys across diverse sacred landscapes. He recently joined ShopAyahuascaRetreats as a Contributing Writer.